{"id":35907,"date":"2026-04-20T11:55:18","date_gmt":"2026-04-20T09:55:18","guid":{"rendered":"https:\/\/www.azzurrodigitale.com\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/"},"modified":"2026-04-20T14:23:57","modified_gmt":"2026-04-20T12:23:57","slug":"digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific","status":"publish","type":"post","link":"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/","title":{"rendered":"Digital as a competitive lever in the Pharma world: the challenge of Thermo Fisher Scientific"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indice dei contenuti<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #21bdff;color:#21bdff\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #21bdff;color:#21bdff\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/#A_journey_that_started_a_long_time_ago\" >A journey that started a long time ago<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/#Why_the_pharmaceutical_industry_can_no_longer_afford_to_delay\" >Why the pharmaceutical industry can no longer afford to delay<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/#Where_are_investments_being_made\" >Where are investments being made?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/#The_real_challenges_compliance_data_and_skills\" >The real challenges: compliance, data, and skills<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.azzurrodigitale.com\/en\/digital-as-a-competitive-lever-in-the-pharma-world-the-challenge-of-thermo-fisher-scientific\/#A_model_for_the_industry\" >A model for the industry<\/a><\/li><\/ul><\/nav><\/div>\n\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"35907\" class=\"elementor elementor-35907 elementor-35877\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-28203906 e-flex e-con-boxed e-con e-parent\" data-id=\"28203906\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-37c50b33 elementor-widget elementor-widget-text-editor\" data-id=\"37c50b33\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Interview with Riccardo Picca, Senior Director, Digital Transformation &amp; Business Excellence, Drug Product Division \u2013 Thermo Fisher Scientific<\/strong><\/p>\n<div class=\"wp-block-spacer\" style=\"height: 20px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<p><em>The pharmaceutical sector is paying the price for years of digital lag, but competitive pressure and new customer demands are changing the rules of the game. Riccardo Picca from Thermo Fisher Scientific shares an insider\u2019s perspective on how a pharmaceutical manufacturing plant is transforming in the age of artificial intelligence. <\/em><\/p>\n<div class=\"wp-block-spacer\" style=\"height: 60px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<p>In the pharmaceutical sector, digital transformation is no longer an option, but an essential condition for sustaining long-term growth and profitability.<br>This is the view of <strong>Riccardo Picca<\/strong>, Senior Director Digital Transformation &amp; Business Excellence, Drug Product Division at <strong>Thermo Fisher Scientific<\/strong>. With a strong background in Operations and industrial strategy, he currently works at Thermo Fisher Scientific, one of the world\u2019s leading <strong>contract development and manufacturing organizations (CDMOs) <\/strong>for pharmaceuticals.<br>Interviewed for the \u201c<em>factoryvoice<\/em>\u201d column, Picca shares a 360-degree perspective on why\u2014and how\u2014the sector is finally accelerating its shift toward digitalization. <\/p>\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"995\" class=\"wp-image-35881\" style=\"width: 577px; height: auto;\" src=\"https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-1024x995.jpg\" alt=\"\" data-cmp-info=\"10\" srcset=\"https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-1024x995.jpg 1024w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-300x291.jpg 300w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-768x746.jpg 768w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-1536x1492.jpg 1536w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/2024_12_20_PM_045-1-2-2048x1990.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<div class=\"wp-block-spacer\" style=\"height: 30px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_journey_that_started_a_long_time_ago\"><\/span><strong>A journey that started a long time ago<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Before joining Thermo Fisher Scientific in December 2024, Riccardo Picca led digital transformation and business excellence initiatives in complex industrial environments, including <strong>Sandvik<\/strong>, a Swedish multinational with approximately \u20ac10 billion in revenue, where he drove the digital transformation and operational excellence of several manufacturing sites.<br>In parallel, he joined the board of <strong>MIMA<\/strong>, a technical committee sponsored by Microsoft and Roland Berger, with the aim of building a community of knowledge around digitalization in manufacturing across Europe and the Middle East. <\/p>\n<p><em>\u201cWe are involved both in assessing the digital maturity of the companies that apply to join this community, and in sharing best practices, organizing plant visits, and creating training sessions on the issues that can be solved through digitalization in Operations.\u201d<\/em><\/p>\n<p>From these experiences\u2014cross-sector yet always focused on manufacturing\u2014emerges an \u201cagnostic\u201d view of digital applied to Operations, which Riccardo Picca brings today to Thermo Fisher Scientific, in a <strong>division of approximately \u20ac3 billion<\/strong> that manages <strong>16 plants worldwide<\/strong> and produces pharmaceutical products.&nbsp;<\/p>\n<div class=\"wp-block-spacer\" style=\"height: 30px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_the_pharmaceutical_industry_can_no_longer_afford_to_delay\"><\/span><strong>Why the pharmaceutical industry can no longer afford to delay<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The pharmaceutical sector has traditionally been considered <strong>more conservative than other industrial fields when it comes to digital innovation<\/strong>, due to strict regulatory constraints and the need to ensure product safety. Yet today, something is changing profoundly. Riccardo Picca identifies <strong>three major drivers<\/strong>.  <\/p>\n<h4 class=\"wp-block-heading\"><strong>1. Traditional levers are no longer enough<\/strong><\/h4>\n<p>Traditional levers\u2014automation, process engineering, and continuous improvement\u2014are reaching their structural limits.<br>In a context where the demand for medicines exceeds supply, driven by population aging and the global expansion of access to healthcare, productivity must be sought elsewhere. As Riccardo Picca explains, productivity always has two dimensions: <\/p>\n<p><em>&#8220;<\/em><strong><em>Productivity has two dimensions: increasing capacity and reducing costs. Both are becoming increasingly difficult to achieve with traditional tools. <\/em><\/strong><strong><em><br><\/em><\/strong><em>For this reason, a new one must be activated: digitalization.&#8221;<\/em><\/p>\n<h4 class=\"wp-block-heading\"><strong>2. Competitive pressure<\/strong><\/h4>\n<p>The second driver is <strong>competition<\/strong>: rivals are investing, and those who fail to keep pace risk being pushed out of the market. The numbers are clear: in the past, IT and digital spending in pharmaceutical companies was around 0.5% of revenue; today, to remain competitive, it is about 4%.<br>\u201c<em>To stay competitive, <\/em><strong><em>investments will need to reach up to 7% of revenue<\/em><\/strong>,\u201d Riccardo Picca explains. \u201c<em>Digital transformation requires significant investment, not only in technology but also in skills.<\/em>\u201d<br> <br> <br> <\/p>\n<h4 class=\"wp-block-heading\"><strong>3. The relevance of the market<\/strong><\/h4>\n<p>The third driver concerns <strong>how Big Pharma perceives their CDMO partners<\/strong>. Life science industry research shows that over the past five years, buying factors related to digitalization have increased in importance by around 150%.<br>Riccardo Picca\u2019s message is direct: \u201cIn the future, a non-digitalized CDMO\u2014both internally and in its interaction with customers\u2014will no longer be perceived as a strategic partner.\u201d  <\/p>\n<div class=\"wp-block-spacer\" style=\"height: 30px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Where_are_investments_being_made\"><\/span><strong>Where are investments being made?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The areas of digital intervention at Thermo Fisher Scientific are multiple and interconnected, and span the entire value chain.<\/p>\n<h4 class=\"wp-block-heading\"><strong>OEE, scheduling, and predictive maintenance<\/strong><\/h4>\n<p>The starting point is the improvement of <strong><a href=\"https:\/\/www.azzurrodigitale.com\/en\/oee-what-it-is-how-to-calculate-it-and-how-to-improve-it\/\">Overall Equipment Effectiveness<\/a> (OEE)<\/strong> in production lines, both continuous (vial and syringe filling) and discrete (tablets and blisters). Advanced digital systems enable <strong>prescriptive and predictive analysis of losses<\/strong>: setup, changeovers, unplanned maintenance, and quality rejects.<br>\u201c<em>This frees up capacity and reduces costs, because it is cheaper to keep the lines running<\/em>,\u201d explains Riccardo Picca.<br>Alongside this, <strong>production scheduling optimization<\/strong> plays a key role: in pharmaceutical production campaigns, numerous format and product changeovers fragment the flow; optimizing batch sequencing means recovering valuable hours.<br>On the maintenance side, spectral analysis of vibrations on rotating machinery makes it possible to predict component life cycles, reducing costs and unplanned downtime.   <\/p>\n<h4 class=\"wp-block-heading\"><strong>Quality Management System and AI agents<\/strong><\/h4>\n<p>In the pharmaceutical world, any deviation from expected processes triggers a \u201cdeviation\u201d: a long, document-heavy, and highly procedural workflow. A process that Riccardo Picca has chosen as a testing ground for <strong>generative artificial intelligence<\/strong>. <\/p>\n<p><em>\u201cWe are developing solutions with an <strong>orchestrator that coordinates multiple sub-agents to manage deviation management<\/strong> throughout its entire lifecycle: from deviation authoring, to root cause definition, to solution development, to verifying that the implemented solution is effective, all the way to the closure of the deviation itself.\u201d<\/em><br> <br> <br><\/p>\n<h4 class=\"wp-block-heading\"><strong>Paperless: from batch records to laboratories<\/strong><\/h4>\n<p>Each production batch today is accompanied by a <strong>paper batch record<\/strong> of around 1,000 pages, stored for years in secure physical archives. Digitalization does not simply mean creating PDFs: \u201cI<em>t means automatically capturing data, using it to enrich the batch record, avoiding errors and reducing both the manual effort of writing and that of the reviewer\u2014and this also leads to a reduction in deviations and complaints<\/em>,\u201d explains Riccardo Picca.<br>The same principle applies to quality control laboratories, where test results can be automatically captured to speed up batch release and, consequently, release to the customer and the monetization of production. <\/p>\n<h4 class=\"wp-block-heading\"><strong>Energy management, warehouse operations, and working capital<\/strong><\/h4>\n<p>The picture is completed by systems based on <strong>operations research and AI to optimize the energy consumption of production lines<\/strong>, combining production data, weather forecasts, and the characteristics of the product being processed, as well as inventory management through virtual warehouses.<br>The latter goes hand in hand with reducing batch time-to-release: the faster the product is released, the sooner the company gets paid, optimizing the entire order-to-cash cycle. <\/p>\n<div class=\"wp-block-spacer\" style=\"height: 30px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img decoding=\"async\" width=\"807\" height=\"600\" class=\"wp-image-35882\" style=\"aspect-ratio: 1.3450323122996901; width: 615px; height: auto;\" src=\"https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/Thermo-Fisher-Scientific-Patheon-2-jpg.webp\" alt=\"\" data-cmp-info=\"10\" srcset=\"https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/Thermo-Fisher-Scientific-Patheon-2-jpg.webp 807w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/Thermo-Fisher-Scientific-Patheon-2-jpg-300x223.webp 300w, https:\/\/www.azzurrodigitale.com\/wp-content\/uploads\/2026\/04\/Thermo-Fisher-Scientific-Patheon-2-jpg-768x571.webp 768w\" sizes=\"(max-width: 807px) 100vw, 807px\" \/><\/figure>\n<div class=\"wp-block-spacer\" style=\"height: 20px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_real_challenges_compliance_data_and_skills\"><\/span><strong>The real challenges: compliance, data, and skills<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h4 class=\"wp-block-heading\"><strong>Compliance as a structural constraint<\/strong><\/h4>\n<p>The pharmaceutical sector is subject to <strong>GMP regulations that require constant human oversight over any production process<\/strong>. This means that artificial intelligence systems, however sophisticated, cannot operate autonomously on production lines. \u201c<em>There must always be human review and decision-making<\/em>,\u201d explains Riccardo Picca: in the pharmaceutical world, <em>humans in the loop<\/em> are not a design choice, but a necessary regulatory requirement. <\/p>\n<h4 class=\"wp-block-heading\"><strong>The data problem<\/strong><\/h4>\n<p>A crucial technical challenge concerns <strong>data quality and structure<\/strong>. Many pharmaceutical companies have not invested in building a <strong>standardized data layer<\/strong> that normalizes and contextualizes data coming from different machines and production lines: without this infrastructure, digital solutions retrieve data directly from equipment, with significant scalability limitations.<br>For Riccardo Picca, building this layer does not bring immediate productivity gains,  <\/p>\n<p><em><br>\u201cbut it is a strongly enabling factor for development that is not tactical, but strategic. It is one of the major challenges: investing in the creation of a modern tech stack that goes through structured, standardized, and contextualized data management.\u201d<\/em><\/p>\n<h4 class=\"wp-block-heading\"><strong>Change starts with people<\/strong><\/h4>\n<p>Perhaps the most underestimated challenge is the human one. The technology exists, and <strong>people no longer oppose digital innovation on ideological grounds<\/strong>. The real bottleneck <strong>is skills<\/strong>: the pharmaceutical sector, which in the past did not invest heavily in this area, must now quickly close the gap through internal training, recruiting, and the use of external partners.<br>But the starting point, Riccardo Picca warns, is never technology:<br> <br> <br>   <\/p>\n<p><em>\u201cYou have to start from the business need and understand what the right lever is: it may not be digital, it could be a continuous improvement activity or a process redesign. Only after that do you choose the technology, not the other way around. The biggest issue is adoption and change management: not so much convincing people, but giving them the tools to be able to do it.\u201d<\/em><\/p>\n<div class=\"wp-block-spacer\" style=\"height: 30px;\" aria-hidden=\"true\">&nbsp;<\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_model_for_the_industry\"><\/span><strong>A model for the industry<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The experience of Thermo Fisher Scientific, as told by Riccardo Picca, offers a clear snapshot of <strong>what it means to lead digital transformation in a complex sector such as pharmaceuticals<\/strong>: not chasing technological trends, but methodically building an enabling infrastructure made of data, skills, and culture, capable of sustaining profitable growth over time.<br>In a market where digital maturity determines the choice of partners, digital is no longer a competitive advantage. It is an entry requirement. It is the present.   <\/p>\n<p><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Riccardo Picca from Thermo Fisher Scientific explains how the pharmaceutical industry is accelerating its digital transformation: AI, data, and change management to stay competitive.<\/p>\n","protected":false},"author":2,"featured_media":35903,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[160,162],"tags":[],"class_list":["post-35907","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-digital-transformation-en","category-people-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Digital as a competitive lever in Pharma - AzzurroDigitale<\/title>\n<meta name=\"description\" content=\"How 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